Advances in Plant Glycosides, Chemistry and Biology, by Chong-Ren Yang, Osamu Tanaka

By Chong-Ren Yang, Osamu Tanaka

Hardbound. within the plant state a number of chemical components happen in a glycoside shape (conjugation with sugar). Glycosides are very important, secondary metabolites. The structural range is as a result of the monstrous quantity of types and stereochemical configurations of the sugar part. Aglycones belong to terpenoid, steroid, flavonoid, quinonoid, lignan, different basic phenolics, and isothiocyanate. even though, organic actions of glycosides are, in lots of instances, vulnerable to the character of sugar moieties, even supposing their aglycone is the same.Since the 80s, plant glycosides were attracting an expanding quantity of curiosity from botanists and phytochemists world-wide for the next purposes: - they're tricky to isolate and purify- they've got an important organic functionality in vegetation and noteworthy organic actions- they seem to be a extremely important source of usual medication, future health nutrition, cosmetics and f

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Ill , , L H2C=:CH S l ~""NH L goitrin:toxicto thyroid S Fig. 3. Progoitrin, glucosynolate from Brassica spp. Antiyeast spirostanol-monodesmosides The deterioration of cooked foods is known to be caused by yeasts. , and Pichia carsonii) and filmforming yeasts (damaging of soy sauce) (Pichia nakazawae, Debaryomyces hansenii and Zygosaccharomyces rouxii) (Table 1). This fraction was also exhibited growth inhibition of some dematophytic yeasts and fungi. Table 1. 5 T. 3 P. 3 Epidermophyton floccosum ***.

In the group pre-treated with the extract of P. notoginseng, only about 45% of mice bore papillomas at 10-12 weeks of promotion, and only 5 papillomas were formed per mouse atter 20 weeks of promotion. In the group post-treated, only 20% of mice bore papillomas at 11 weeks and 65% even at 20 weeks of promotion, and 2-3 papillomas were formed per mouse after 20 weeks of promotion. Therefore, the MeOH extract of P. notoginseng significantly delayed the formation of papillomas and reduced the 38 number of papillomas per mouse.

09% phenobarbital (PB) solution has been drunk as the promotion treatment instead of drinking water. 5 Without initiation, drinking water alone. Further in our experiment, the MeOH extract of P. notoginseng exhibited the strong inhibitory effects on the liver damage of mouse induced by the dioxine derivative, tetrabromodioxine (TBDD). 9These results strongly suggested that P. notoginseng might be a valuable anti-tumorpromoter and chemopreventive agent in chemical carcinogenesis, and that one of the active principles of P.

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